MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0408 · 46 genes shown · anchor ackA · open gene page → · ← back to 1 hop

Evidence: Min score 0
pta (requalified) — phosphate acetyltransferase pta ackA (requalified) — acetate kinase ackA glcB (requalified) — malate synthase G glcB Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC acs (requalified) — acetate--CoA ligase acs Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c mmsA (requalified) — CoA-acylating methylmalonate-semialdehyde dehydrog mmsA TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 acyP (requalified) — acylphosphatase acyP fadA3 (requalified) — acetyl-CoA C-acetyltransferase fadA3 Rv0914c (requalified) — acetyl-CoA acetyltransferase Rv0914c fadA4 (requalified) — acetyl-CoA acetyltransferase fadA4 pcd (requalified) — piperideine-6-carboxylic acid dehydrogenase pcd aldA (requalified) — aldehyde dehydrogenase aldA Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 Rv0223c (requalified) — aldehyde dehydrogenase Rv0223c icl1 (requalified) — isocitrate lyase icl1 aceAa (requalified) — isocitrate lyase AceAa aceAa aceAb (requalified) — isocitrate lyase AceAb aceAb gltA2 (requalified) — citrate synthase gltA2 icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC aceE (requalified) — pyruvate dehydrogenase E1 component aceE Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 prpC (requalified) — 2-methylcitrate synthase prpC citA (requalified) — citrate synthase 2 citA Rv0147 (requalified) — aldehyde dehydrogenase Rv0147 mobA (requalified) — molybdenum cofactor guanylyltransferase mobA pykA (requalified) — pyruvate kinase pykA mmsB (requalified) — 3-hydroxyisobutyrate dehydrogenase mmsB fadE9 (family_assigned) — acyl-CoA dehydrogenase family protein fadE9 gabT (requalified) — 4-aminobutyrate--2-oxoglutarate transaminase gabT accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 leuA (requalified) — 2-isopropylmalate synthase leuA Rv3175 (requalified) — amidase Rv3175 amiB2 (requalified) — amidase amiB2 amiA2 (requalified) — amidase amiA2 amiD (requalified) — amidase amiD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.