Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0384c · 45 genes shown · anchor pyrE · open gene page → · ← back to 1 hop

Evidence: Min score 0
clpB (requalified) — chaperone protein ClpB clpB dnaK (requalified) — molecular chaperone DnaK dnaK grpE (requalified) — nucleotide exchange factor GrpE grpE clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 hsp (requalified) — stress-responsive chaperone Acr2 hsp Rv0987 (family_assigned) — FtsX-like permease family protein Rv0987 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 hspR (family_assigned) — heat shock transcriptional regulator HspR hspR htpG (requalified) — molecular chaperone HtpG htpG groEL2 (requalified) — chaperonin GroEL groEL2 Rv1332 (family_assigned) — transcriptional regulator Rv1332 Rv1333 (family_assigned) — P1 family peptidase Rv1333 mec (requalified) — CysO-cysteine peptidase mec clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 clpC2 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC2 clpX (family_assigned) — ATP-dependent Clp protease ATP-binding subunit Clp clpX tig (requalified) — trigger factor tig Rv3716c (family_assigned) — YbaB/EbfC family nucleoid-associated protein Rv3716c groEL1 (requalified) — chaperonin GroEL groEL1 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 pirG (requalified) — exported repetitive protein pirG Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c groES (requalified) — chaperonin GroES groES nirD (family_assigned) — nitrite reductase small subunit NirD nirD fxsA (family_assigned) — FxsA family protein fxsA Rv0988 (family_assigned) — lipocalin-like domain-containing protein Rv0988 Rv0986 (family_assigned) — ABC transporter ATP-binding protein Rv0986 moeW (family_assigned) — ThiF family adenylyltransferase moeW mscL (requalified) — large-conductance mechanosensitive channel protein mscL glnQ (family_assigned) — ATP-binding cassette domain-containing protein glnQ Rv0385 (requalified) — FAD-binding oxidoreductase Rv0385 Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 pyrE (requalified) — orotate phosphoribosyltransferase pyrE pyrD (requalified) — quinone-dependent dihydroorotate dehydrogenase pyrD carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB Rv0381c (dark) — hypothetical protein Rv0381c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.