MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0357c · 46 genes shown · anchor guaA · open gene page → · ← back to 1 hop

Evidence: Min score 0
purA (requalified) — adenylosuccinate synthase purA purB (requalified) — adenylosuccinate lyase purB guaB2 (requalified) — IMP dehydrogenase guaB2 guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 Rv0356c (family_assigned) — PaaI family thioesterase Rv0356c pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB argG (requalified) — argininosuccinate synthase argG hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt asnB (requalified) — asparagine synthase (glutamine-hydrolyzing) asnB guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA nadB (requalified) — L-aspartate oxidase nadB purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC apt (requalified) — adenine phosphoribosyltransferase apt adk (requalified) — adenylate kinase adk fas (requalified) — fatty acid synthase fas rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB purN (requalified) — phosphoribosylglycinamide formyltransferase purN glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 Rv2042c (family_assigned) — ketosteroid isomerase family protein Rv2042c Rv3035 (family_assigned) — hypothetical protein Rv3035 Rv0358 (requalified) — peptidase M50 Rv0358 carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA pyrC (requalified) — dihydroorotase pyrC carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF Rv1382 (requalified) — transporter Rv1382 argH (requalified) — argininosuccinate lyase argH argF (requalified) — ornithine carbamoyltransferase argF argB (requalified) — acetylglutamate kinase argB argD (requalified) — acetylornithine transaminase argD argJ (requalified) — bifunctional glutamate N-acetyltransferase/amino-a argJ argR (requalified) — arginine repressor argR mesJ (requalified) — tRNA lysidine(34) synthetase TilS mesJ deoD (requalified) — purine-nucleoside phosphorylase deoD Rv1021 (requalified) — nucleoside triphosphate pyrophosphohydrolase Rv1021 ansA (requalified) — asparaginase ansA ask (requalified) — aspartate kinase ask argS (requalified) — arginine--tRNA ligase argS rplK (requalified) — 50S ribosomal protein L11 rplK

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.