MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0356c · 46 genes shown · anchor purA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0356c (family_assigned) — PaaI family thioesterase Rv0356c purA (requalified) — adenylosuccinate synthase purA mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 Rv2042c (family_assigned) — ketosteroid isomerase family protein Rv2042c Rv3035 (family_assigned) — hypothetical protein Rv3035 Rv0358 (requalified) — peptidase M50 Rv0358 fas (requalified) — fatty acid synthase fas Rv3531c (family_assigned) — hypothetical protein Rv3531c Rv1780 (family_assigned) — hypothetical protein Rv1780 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv2876 (requalified) — transmembrane protein Rv2876 Rv0359 (family_assigned) — site-2 protease family protein Rv0359 purB (requalified) — adenylosuccinate lyase purB guaB2 (requalified) — IMP dehydrogenase guaB2 guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ephC (requalified) — epoxide hydrolase EphC ephC pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pncA (requalified) — pyrazinamidase PncA pncA Rv2041c (family_assigned) — sugar ABC transporter substrate-binding protein Rv2041c Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c lprC (family_assigned) — DUF3558 domain-containing protein lprC lprB (family_assigned) — DUF3558 domain-containing protein lprB Rv1476 (family_assigned) — DUF6676 family protein Rv1476 Rv3802c (requalified) — phospholipase Rv3802c aftA (requalified) — galactan 5-O-arabinofuranosyltransferase aftA Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv3217c (dark) — hypothetical protein Rv3217c pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 mas (requalified) — mycocerosate synthase mas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.