Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0293c · 46 genes shown · anchor tam · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0293c (requalified) — alpha/beta fold hydrolase Rv0293c tam (requalified) — trans-aconitate 2-methyltransferase tam Rv1874 (family_assigned) — hypothetical protein Rv1874 pirG (requalified) — exported repetitive protein pirG lipE (requalified) — lipase LipE lipE Rv2913c (family_assigned) — amidohydrolase family protein Rv2913c mprB (requalified) — two-component system sensor histidine kinase MprB mprB Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2910c (family_assigned) — hypothetical protein Rv2910c Rv2484c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv2484c lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv0518 (family_assigned) — SGNH/GDSL hydrolase family protein Rv0518 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv2628 (dark) — hypothetical protein Rv2628 Rv0987 (family_assigned) — FtsX-like permease family protein Rv0987 esxR (family_assigned) — WXG100 family type VII secretion target esxR Rv1769 (requalified) — amino acid deaminase/aldolase Rv1769 Rv0988 (family_assigned) — lipocalin-like domain-containing protein Rv0988 Rv1875 (requalified) — PPOX class F420-dependent oxidoreductase Rv1875 Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c Rv3577 (requalified) — hypothetical protein Rv3577 Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA Rv1158c (dark) — hypothetical protein Rv1158c mtc28 (family_assigned) — LpqN/LpqT family lipoprotein mtc28 echA21 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA21 Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c Rv1780 (family_assigned) — hypothetical protein Rv1780 Rv2285 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv2285 Rv3480c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3480c Rv2912c (family_assigned) — TetR/AcrR family transcriptional regulator Rv2912c pknI (requalified) — serine/threonine protein kinase PknI pknI ffh (requalified) — signal recognition particle protein ffh Rv2915c (family_assigned) — amidohydrolase family protein Rv2915c mprA (requalified) — two-component system response regulator MprA mprA pepD (requalified) — serine protease PepD pepD prrA (requalified) — two-component system response regulator PrrA prrA tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA trcR (requalified) — two-component system response regulator TrcR trcR tcrX (requalified) — two-component system response regulator TcrX tcrX eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 htpG (requalified) — molecular chaperone HtpG htpG

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.