Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0280 · 31 genes shown · anchor eccA3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE3 (family_assigned) — PPE family protein PPE3 PPE3 Rv2990c (requalified) — class I SAM-dependent methyltransferase Rv2990c eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 Rv0106 (family_assigned) — GTP-binding protein Rv0106 rpmB2 (requalified) — 50S ribosomal protein L28 rpmB2 Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 Rv2059 (family_assigned) — hypothetical protein Rv2059 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 PE5 (family_assigned) — PE family protein PE5 PE5 PE_PGRS4 (family_assigned) — PE-PGRS family protein PE_PGRS4 PE_PGRS4 esxG (requalified) — type VII secretion system protein EsxG esxG rpsN2 (requalified) — 30S ribosomal protein S14 rpsN2 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 rpmG1 (requalified) — 50S ribosomal protein L33 rpmG1 rpsR2 (requalified) — 30S ribosomal protein S18 rpsR2 rplI (requalified) — 50S ribosomal protein L9 rplI rpmF (requalified) — 50S ribosomal protein L32 rpmF rpsF (requalified) — 30S ribosomal protein S6 rpsF Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 Rv2060 (family_assigned) — integral membrane protein Rv2060 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 Rv0278c (family_assigned) — PE-PGRS family protein PE_PGRS3 Rv0278c zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 Rv3213c (family_assigned) — AAA family ATPase Rv3213c esxH (requalified) — type VII secretion system effector EsxH esxH esxR (family_assigned) — WXG100 family type VII secretion target esxR esxQ (requalified) — type VII secretion system ESX-3 effector EsxQ esxQ

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.