MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0279c · 43 genes shown · anchor PE_PGRS3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE_PGRS4 (family_assigned) — PE-PGRS family protein PE_PGRS4 PE_PGRS4 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 Rv0278c (family_assigned) — PE-PGRS family protein PE_PGRS3 Rv0278c PPE3 (family_assigned) — PPE family protein PPE3 PPE3 zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 Rv3213c (family_assigned) — AAA family ATPase Rv3213c Rv2813 (family_assigned) — ExeA family protein Rv2813 Rv3212 (family_assigned) — hypothetical protein Rv3212 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH lppA (family_assigned) — LppA family lipoprotein lppA PPE22 (family_assigned) — PPE family protein PPE22 PPE22 lppB (family_assigned) — LppA family lipoprotein lppB eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 pknD (requalified) — serine/threonine protein kinase PknD pknD lppD (requalified) — lipoprotein LppD lppD Rv2990c (requalified) — class I SAM-dependent methyltransferase Rv2990c Rv0106 (family_assigned) — GTP-binding protein Rv0106 rpmB2 (requalified) — 50S ribosomal protein L28 rpmB2 Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 Rv2059 (family_assigned) — hypothetical protein Rv2059 omamA (requalified) — hypothetical protein omamA omamB (requalified) — hypothetical protein omamB polA (requalified) — DNA polymerase I polA ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB Rv3633 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv3633 Rv1501 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv1501 parB (family_assigned) — ParB/RepB/Spo0J family partition protein parB entC (requalified) — isochorismate synthase entC gpm2 (requalified) — phosphoglycerate mutase gpm2 Rv2647 (requalified) — hypothetical protein Rv2647 ftsK (requalified) — DNA translocase FtsK ftsK dnaA (requalified) — chromosomal replication initiator protein DnaA dnaA Rv2812 (family_assigned) — helix-turn-helix domain-containing protein Rv2812 Rv3638 (family_assigned) — ATP-binding protein Rv3638 Rv2811 (family_assigned) — hypothetical protein Rv2811 gltB (family_assigned) — glutamate synthase large subunit gltB rhlE (requalified) — DEAD/DEAH box helicase rhlE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.