Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0278c · 45 genes shown · anchor vapB25 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0278c (family_assigned) — PE-PGRS family protein PE_PGRS3 Rv0278c vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 PE_PGRS4 (family_assigned) — PE-PGRS family protein PE_PGRS4 PE_PGRS4 zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 pknD (requalified) — serine/threonine protein kinase PknD pknD lppD (requalified) — lipoprotein LppD lppD Rv0311 (family_assigned) — hypothetical protein Rv0311 cpdA (requalified) — 3'%2C5'-cyclic adenosine monophosphate phosphodies cpdA PPE58 (family_assigned) — PPE family protein PPE58 PPE58 PE_PGRS49 (family_assigned) — PE-PGRS family protein PE_PGRS49 PE_PGRS49 PPE53 (family_assigned) — PPE family protein PPE53 PPE53 galTb (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTb vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 vapC48 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC48 vapB31 (family_assigned) — ribbon-helix-helix protein%2C CopG family vapB31 vapB43 (family_assigned) — ribbon-helix-helix domain-containing protein vapB43 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 PPE3 (family_assigned) — PPE family protein PPE3 PPE3 Rv3213c (family_assigned) — AAA family ATPase Rv3213c omamA (requalified) — hypothetical protein omamA omamB (requalified) — hypothetical protein omamB polA (requalified) — DNA polymerase I polA ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB Rv3633 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv3633 Rv1501 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv1501 pstP (requalified) — phosphoserine/threonine phosphatase PstP pstP pstS2 (family_assigned) — phosphate ABC transporter substrate-binding lipopr pstS2 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB qcrC (requalified) — cytochrome c qcrC Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 garA (requalified) — glycogen accumulation regulator GarA garA lipJ (family_assigned) — adenylate/guanylate cyclase domain-containing prot lipJ cobB (requalified) — NAD-dependent protein deacylase cobB cinA (requalified) — competence/damage-inducible protein A cinA Rv2972c (family_assigned) — HNH endonuclease family protein Rv2972c Rv0143c (requalified) — chloride channel protein Rv0143c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c Rv0771 (family_assigned) — carboxymuconolactone decarboxylase family protein Rv0771 Rv0762c (family_assigned) — nuclear transport factor 2 family protein Rv0762c Rv0767c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0767c Rv0765c (family_assigned) — SDR family oxidoreductase Rv0765c cyp51 (requalified) — lanosterol 14-alpha demethylase cyp51 apt (requalified) — adenine phosphoribosyltransferase apt adoK (family_assigned) — carbohydrate kinase family protein adoK

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.