MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0269c · 46 genes shown · anchor ligC · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0269c (requalified) — DNA polymerase domain-containing protein Rv0269c ligC (requalified) — ATP-dependent DNA ligase ligC mku (requalified) — Ku protein mku ligB (requalified) — ATP-dependent DNA ligase ligB Rv0268c (family_assigned) — hypothetical protein Rv0268c fadD2 (requalified) — long-chain-fatty-acid--CoA ligase FadD2 fadD2 Rv0265c (family_assigned) — iron ABC transporter substrate-binding lipoprotein Rv0265c Rv0264c (family_assigned) — allophanate hydrolase subunit 1 Rv0264c Rv2828A (dark) — hypothetical protein Rv2828A lhr (requalified) — ATP-dependent helicase lhr Rv0263c (family_assigned) — 5-oxoprolinase/urea amidolyase family protein Rv0263c Rv3662c (requalified) — oxidoreductase Rv3662c Rv2515c (family_assigned) — XRE family transcriptional regulator Rv2515c ligD (requalified) — non-homologous end-joining DNA ligase ligD lppK (family_assigned) — hypothetical protein lppK dnaN (family_assigned) — DNA polymerase III subunit beta dnaN Rv2090 (requalified) — 5'-3' exonuclease Rv2090 ligD (requalified) — ATP-dependent DNA ligase ligD uvrD1 (requalified) — ATP-dependent DNA helicase UvrD uvrD1 ligA (requalified) — NAD-dependent DNA ligase LigA ligA polA (requalified) — DNA polymerase I polA fadE22 (requalified) — acyl-CoA dehydrogenase fadE22 relK (family_assigned) — Txe/YoeB family addiction module toxin relK Rv0366c (family_assigned) — zeta toxin family protein Rv0366c mazE3 (requalified) — antitoxin MazE3 mazE3 Rv2017 (family_assigned) — ImmA/IrrE family metallo-endopeptidase Rv2017 rplF (requalified) — 50S ribosomal protein L6 rplF pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC oplA (family_assigned) — hydantoinase B/oxoprolinase family protein oplA aac (requalified) — aminoglycoside 2'-N-acetyltransferase aac fecB (family_assigned) — iron-siderophore ABC transporter substrate-binding fecB Rv1289 (family_assigned) — hypothetical protein Rv1289 Rv1249c (family_assigned) — hypothetical protein Rv1249c oprA (requalified) — osmosensory protein OprA oprA Rv1773c (family_assigned) — IclR family transcriptional regulator Rv1773c Rv2828c (family_assigned) — DUF1802 family protein Rv2828c vapB22 (family_assigned) — type II toxin-antitoxin system prevent-host-death vapB22 vapC22 (family_assigned) — PIN domain-containing protein vapC22 echA16 (requalified) — enoyl-CoA hydratase echA16 Rv1156 (requalified) — HhH-GPD-type base excision DNA repair protein Rv1156 nei (requalified) — endonuclease VIII Nei2 nei Rv3295 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3295

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.