MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0256c · 46 genes shown · anchor cobQ1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE2 (family_assigned) — PPE family protein PPE2 PPE2 cobQ1 (requalified) — cobyric acid synthase cobQ1 pirG (requalified) — exported repetitive protein pirG eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0479c (family_assigned) — DUF2993 domain-containing protein Rv0479c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv0955 (family_assigned) — DUF6350 family protein Rv0955 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 PPE64 (family_assigned) — PPE family protein PPE64 PPE64 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU cobD (requalified) — cobalamin biosynthesis protein cobD cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobH (requalified) — precorrin-8X methylmutase cobH cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA Rv1158c (dark) — hypothetical protein Rv1158c mtc28 (family_assigned) — LpqN/LpqT family lipoprotein mtc28 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 htpG (requalified) — molecular chaperone HtpG htpG mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 Rv0480c (family_assigned) — carbon-nitrogen hydrolase family protein Rv0480c Rv0481c (family_assigned) — DUF2505 domain-containing protein Rv0481c Rv0227c (family_assigned) — membrane protein Rv0227c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.