MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0190 · 46 genes shown · anchor ilvD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0190 (family_assigned) — metal-sensitive transcriptional regulator Rv0190 ilvD (requalified) — dihydroxy-acid dehydratase ilvD Rv0191 (family_assigned) — Rv0191 family MFS efflux transporter Rv0191 mscR (requalified) — S-(hydroxymethyl)mycothiol dehydrogenase mscR adhD (requalified) — NDMA-dependent alcohol dehydrogenase adhD adhB (requalified) — alcohol dehydrogenase B adhB adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1 Rv0192 (family_assigned) — hypothetical protein Rv0192 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC fbpA (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpA Rv1288 (requalified) — esterase Rv1288 Rv0774c (requalified) — iron-stress inducible esterase Rv0774c Rv1639c (family_assigned) — alpha/beta hydrolase family protein Rv1639c ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvE (requalified) — branched-chain amino acid aminotransferase ilvE leuA (requalified) — 2-isopropylmalate synthase leuA ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC Rv1667c (family_assigned) — Probable second part of macrolide-transport ATP-bi Rv1667c proZ (family_assigned) — glycine betaine/carnitine/choline/L-proline ABC tr proZ pdxH (requalified) — pyridoxamine 5'-phosphate oxidase pdxH Rv2260 (requalified) — MBL fold metallo-hydrolase Rv2260 Rv2258c (requalified) — class I SAM-dependent methyltransferase Rv2258c Rv2257c (family_assigned) — serine hydrolase domain-containing protein Rv2257c Rv3083 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv3083 lipR (family_assigned) — alpha/beta hydrolase lipR Rv3085 (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv3085 fadD13 (requalified) — long-chain-fatty-acid--CoA ligase FadD13 fadD13 tgs4 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr tgs4 Rv3087 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3087 Rv0760c (family_assigned) — ketosteroid isomerase family protein Rv0760c aldA (requalified) — aldehyde dehydrogenase aldA Rv0147 (requalified) — aldehyde dehydrogenase Rv0147 pcd (requalified) — piperideine-6-carboxylic acid dehydrogenase pcd Rv0223c (requalified) — aldehyde dehydrogenase Rv0223c Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 dhaA (requalified) — haloalkane dehalogenase dhaA Rv3015c (requalified) — methionine synthase Rv3015c dacB1 (requalified) — D-alanyl-D-alanine carboxypeptidase DacB1 dacB1 dacB2 (family_assigned) — penicillin-binding protein DacB2 dacB2 ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 ponA1 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA1 fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB lipY (requalified) — triacylglycerol lipase Lip lipY Rv2252 (requalified) — diacylglycerol kinase Rv2252

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.