MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0177 · 43 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0177 (requalified) — Mce associated protein Rv0177 Rv0178 (requalified) — Mce associated membrane protein Rv0178 Rv0175 (family_assigned) — hypothetical protein Rv0175 Rv0176 (family_assigned) — RDD family protein Rv0176 pks12 (requalified) — type I polyketide synthase pks12 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv2267c (requalified) — sulfotransferase Rv2267c pks17 (requalified) — polyketide synthase pks17 mce1F (family_assigned) — MCE family protein mce1F mce1C (family_assigned) — MCE family protein mce1C phoY1 (requalified) — phosphate signaling complex protein PhoU phoY1 mce1B (family_assigned) — virulence factor Mce family protein mce1B mce1D (family_assigned) — virulence factor Mce family protein mce1D mce1A (family_assigned) — Mce family protein Mce1A mce1A fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB papA1 (requalified) — acyltransferase PapA1 papA1 Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c Rv3531c (family_assigned) — hypothetical protein Rv3531c htpG (requalified) — molecular chaperone HtpG htpG alaS (requalified) — alanine--tRNA ligase alaS rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF Rv1692 (family_assigned) — HAD-IIA family hydrolase Rv1692 ppnK (requalified) — NAD kinase ppnK tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA Rv1693 (dark) — hypothetical protein Rv1693 cyp128 (requalified) — cytochrome P450 cyp128 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks3 (requalified) — polyketide beta-ketoacyl synthase pks3

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.