MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0166 · 35 genes shown · anchor yrbE1A · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD5 (requalified) — fatty-acid--CoA ligase FadD5 fadD5 yrbE1A (family_assigned) — ABC transporter permease yrbE1A mce1C (family_assigned) — MCE family protein mce1C mce1A (family_assigned) — Mce family protein Mce1A mce1A yrbE1B (family_assigned) — ABC transporter permease yrbE1B mce1D (family_assigned) — virulence factor Mce family protein mce1D lprK (family_assigned) — virulence factor Mce family protein lprK pks15 (requalified) — polyketide synthase pks15 mce1B (family_assigned) — virulence factor Mce family protein mce1B pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 mbtC (requalified) — polyketide synthetase MbtC mbtC fadD11.1 (family_assigned) — Possible fatty-acid-CoA ligase FadD11.1 (fatty-aci fadD11.1 pks17 (requalified) — polyketide synthase pks17 mce1F (family_assigned) — MCE family protein mce1F mkl (family_assigned) — ABC transporter ATP-binding protein mkl pks1 (requalified) — polyketide synthase pks1 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c papA3 (requalified) — acyltransferase PapA3 papA3 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF fadD11 (requalified) — fatty-acid--CoA ligase FadD11 fadD11 lipQ (family_assigned) — alpha/beta hydrolase lipQ plsB1 (requalified) — lysophospholipid acyltransferase plsB1 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 gmk (requalified) — guanylate kinase gmk pks8 (requalified) — polyketide synthase pks8 fas (requalified) — fatty acid synthase fas pks9 (requalified) — type I polyketide synthase pks9

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.