MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0118c · 46 genes shown · anchor ilvN · open gene page → · ← back to 1 hop

Evidence: Min score 0
oxcA (requalified) — oxalyl-CoA decarboxylase oxcA ilvN (family_assigned) — acetolactate synthase small subunit ilvN fadD7 (family_assigned) — FadD7 family fatty acid--CoA ligase fadD7 ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvD (requalified) — dihydroxy-acid dehydratase ilvD htrA (requalified) — serine protease HtrA htrA leuA (requalified) — 2-isopropylmalate synthase leuA pepD (requalified) — serine protease PepD pepD hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE Rv3672c (requalified) — CoA pyrophosphatase Rv3672c aao (requalified) — FAD-dependent oxidoreductase aao icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX leuB (requalified) — 3-isopropylmalate dehydrogenase leuB rplF (requalified) — 50S ribosomal protein L6 rplF pks15 (requalified) — polyketide synthase pks15 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 ilvE (requalified) — branched-chain amino acid aminotransferase ilvE leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC tatB (requalified) — Sec-independent protein translocase protein TatB tatB mpa (requalified) — proteasome ATPase mpa rseA (requalified) — anti-sigma E factor RseA rseA glpK (requalified) — glycerol kinase GlpK glpK mec (requalified) — CysO-cysteine peptidase mec prcB (family_assigned) — proteasome subunit beta prcB hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 moaB2 (family_assigned) — MogA/MoaB family molybdenum cofactor biosynthesis moaB2 mprB (requalified) — two-component system sensor histidine kinase MprB mprB htpX (requalified) — zinc metalloprotease HtpX htpX mprA (requalified) — two-component system response regulator MprA mprA sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE Rv3538 (requalified) — dehydrogenase Rv3538 kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c marP (requalified) — acid resistance serine protease MarP marP

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.