MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0045c · 43 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0045c (family_assigned) — alpha/beta hydrolase Rv0045c Rv0044c (requalified) — LLM class F420-dependent oxidoreductase Rv0044c Rv0043c (family_assigned) — GntR family transcriptional regulator Rv0043c ino1 (requalified) — inositol-3-phosphate synthase ino1 Rv0047c (family_assigned) — PadR family transcriptional regulator Rv0047c Rv0042c (family_assigned) — transcriptional regulator Rv0042c Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks12 (requalified) — type I polyketide synthase pks12 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks1 (requalified) — polyketide synthase pks1 fgd1 (requalified) — glucose-6-phosphate dehydrogenase (coenzyme-F420) fgd1 fgd2 (requalified) — F420-dependent hydroxymycolic acid dehydrogenase fgd2 ddn (requalified) — deazaflavin-dependent nitroreductase Ddn ddn Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 embR (requalified) — response regulator transcription factor EmbR embR moxR2 (family_assigned) — MoxR family ATPase moxR2 Rv3840 (family_assigned) — transcriptional regulator Rv3840 moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 impA (family_assigned) — inositol monophosphatase family protein impA suhB (requalified) — inositol-1-monophosphatase SuhB suhB Rv0650 (family_assigned) — ROK family protein Rv0650 pgmA (requalified) — phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosp pgmA pgsA1 (requalified) — CDP-diacylglycerol--inositol 3-phosphatidyltransfe pgsA1 Rv0049 (dark) — hypothetical protein Rv0049 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c Rv3779 (family_assigned) — DUF6541 family protein Rv3779 Rv1171 (family_assigned) — hypothetical protein Rv1171 Rv0875c (dark) — DUF2771 domain-containing protein Rv0875c Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 Rv0188 (requalified) — SPW repeat protein Rv0188 Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.