MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0035 · 46 genes shown · anchor acpA · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD34 (requalified) — fatty-acid--CoA ligase FadD34 fadD34 acpA (requalified) — acyl carrier protein acpA Rv0034 (family_assigned) — nuclear transport factor 2 family protein Rv0034 bioF2 (family_assigned) — pyridoxal phosphate-dependent aminotransferase fam bioF2 mbtE (requalified) — peptide synthetase mbtE PPE35 (family_assigned) — PPE family protein PPE35 PPE35 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp rplF (requalified) — 50S ribosomal protein L6 rplF mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks6 (requalified) — membrane bound polyketide synthase pks6 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 fas (requalified) — fatty acid synthase fas nuoC (family_assigned) — NADH-quinone oxidoreductase subunit C nuoC nuoB (family_assigned) — NADH-quinone oxidoreductase subunit B nuoB Rv2305 (family_assigned) — hypothetical protein Rv2305 Rv1907c (dark) — hypothetical protein Rv1907c PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 bioA (requalified) — adenosylmethionine--8-amino-7-oxononanoate transam bioA bioF1 (requalified) — 8-amino-7-oxononanoate synthase bioF1 bioD (requalified) — dethiobiotin synthase bioD mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG PPE34 (family_assigned) — PPE family protein PPE34 PPE34 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 PE_PGRS23 (family_assigned) — PE-PGRS family protein PE_PGRS23 PE_PGRS23 Rv1004c (family_assigned) — hypothetical protein Rv1004c PE_PGRS48 (family_assigned) — PE-PGRS family protein PE_PGRS48 PE_PGRS48 PE_PGRS2 (family_assigned) — PE-PGRS family protein PE_PGRS2 PE_PGRS2 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks13 (requalified) — polyketide synthase Pks13 pks13 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 mas (requalified) — mycocerosate synthase mas rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.